By Seon-Kyung Woo, Chang-Beom Park, Seong-Whan Lee (auth.), De-Shuang Huang, Xiao-Ping Zhang, Guang-Bin Huang (eds.)
The overseas convention on clever Computing (ICIC) used to be manage as an annual discussion board devoted to rising and tough issues within the quite a few features of advances in computational intelligence fields, reminiscent of synthetic intelligence, desktop studying, bioinformatics, and computational biology, and so forth. The objective of this convention was once to assemble researchers from academia and in addition to practitioners to percentage principles, difficulties and ideas relating to the multifaceted points of clever computing. This publication constitutes the lawsuits of the overseas convention on clever Computing (ICIC 2005), held in Hefei, Anhui, China, in the course of August 23–26, 2005. ICIC 2005 bought over 2000 submissions from authors in 39 international locations and areas. in keeping with rigorous peer studies, this system Committee chosen 563 top of the range papers for presentation at ICIC 2005; of those, 215 papers have been released during this e-book prepared into nine different types, and the opposite 348 papers have been released in 5 foreign journals. The organizers of ICIC 2005 made nice efforts to make sure the luck of this convention. We right here thank the individuals of the ICIC 2005 Advisory Committee for his or her information and recommendation, the participants of this system Committee and the referees for reviewing the papers, and the individuals of the ebook Committee for checking and compiling the papers. we'd additionally prefer to thank the writer, Springer, for his or her aid in publishing the court cases within the Lecture Notes in computing device technology sequence. relatively, we want to thank all of the authors for contributing their papers.
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Additional info for Advances in Intelligent Computing: International Conference on Intelligent Computing, ICIC 2005, Hefei, China, August 23-26, 2005, Proceedings, Part II
11 – 20, 2005. © Springer-Verlag Berlin Heidelberg 2005 12 W. Wang, Y. Zhou, and R. Bi produce long lists of differentially expressed genes, therefore, they cannot effectively separate the genes causally involved in a disease from innocent bystanders [3,5,10]. It seems reasonable to suppose that the presence of genetic alterations may frequently lead to changing the expression levels of many other genes functionally connected with disease genes . One promising method is to analyze the alterations of gene expression at the functional level, such as biological pathways.
The results of Hua and Sun, Nguyen and Rajapakse were obtained from their papers. Our proposed method showed better results compared to previous methods. This reflected that combined profile of sequence profile and conserved domain profile could improve the prediction accuracy. Protein Secondary Structure Prediction 9 Table 2. 2% Table 3. 9% 5 Conclusions and Further Research Protein secondary structure prediction is one of the most promising research areas in bioinformatics because it provides key information to understand the structures of proteins.
Flowchart of MageKey. The goal of MageKey is to determine whether the expressions of multiple genes within a predefined functional category are consistently altered between two conditions. See text for details. variance will be always considered as non-significant. In Cyber-T, it combines information from gene-specific and global average variance estimates and thus should be more stable. But it will generate bias when the assumption of normal distribution is violated. 5) to determine the relative weights of gene-specific variance and global average variance, and reports its significance by permutation analysis.